5 Amazing Migraine Relief Supplements to Test

5 Amazing Migraine Relief Supplements to Test are all complementary or alternative therapies that have been studied for their potential benefits in reducing the frequency and intensity of migraines. I have personally tried them all with various degrees of relief. As everyone is different I would recommend you to try for yourself. Keep track in a log so you know what works best for you and in which conditions.

Omega-3 fatty acids

Commonly found in fatty fish and certain plant-based oils, can help reduce inflammation and improve brain function. And as consequence may help relieve migraine symptoms.

Benefits to relieve migraines

Omega-3 fatty acids are a type of polyunsaturated fat that are for brain function and inflammation:

1. Anti-inflammatory effects: either the supplement or food rich in Omega 3 can help reduce the inflammation. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have anti-inflammatory effects due to their ability to modulate the production of signaling molecules involved in inflammation. Here’s how it works:
   • Modulation of eicosanoids: competing with and replace the production of pro-inflammatory eicosanoids, which are signaling molecules that regulate inflammation in the body. By replacing these pro-inflammatory eicosanoids with anti-inflammatory ones, omega-3 fatty acids can help reduce inflammation.
   • Regulation of cytokines: helping regulate the production of cytokines, which are signaling proteins that mediate the immune response and contribute to inflammation. By regulating cytokine production, omega-3 fatty acids can help reduce inflammation.
   • Inhibition of Nuclear Factor-κB (NF-κB): may inhibit the activation of Nuclear Factor-κB (NF-κB), a key signaling molecule involved in the regulation of inflammation. By inhibiting NF-κB, omega-3 fatty acids can help reduce inflammation in the body.
2. Improved brain function: helping to improve the function of the brain regions. Here is why:
   • Improving nerve cell communication: helping to regulate the communication between nerve cells. By improving nerve cell communication, omega-3 fatty acids can help improve brain function.
   • Increasing neuroplasticity: promoting the growth and development of new brain cells, a process known as neuroplasticity. By increasing neuroplasticity, omega-3 fatty acids may help improve the function of various brain regions.
   • Enhancing mood: and also reducing symptoms of depression and anxiety, which can have a positive impact on overall brain function.
3. Reduced oxidative stress:
   • Acting as antioxidants: helping to neutralize harmful free radicals that contribute to oxidative stress.
   • Regulating gene expression: regulating the expression of genes in the body’s antioxidant defense system.
   • Modulating immune function: modulating the immune system and reduce the oxidative stress that results from immune system activation.

High-dose creatine

Creatine is a molecule that is naturally present in the body and plays a role in energy production.

Benefits to relieve migraines

Here are a few potential benefits of high-dose creatine for migraines:

1. Improved energy production: and reduce fatigue which is a very common migraine symptom. Overall, creatine supplementation has been shown to increase the body’s ability to produce ATP and support energy production, especially during high-intensity exercise or other energy-demanding activities. This can lead to improved athletic performance, increased energy levels, and enhanced recovery.
2. Improved brain function: increasing the availability of energy in the brain and promoting the synthesis of neurotransmitters, such as dopamine and acetylcholine, which are essential for brain function and play a role in memory, attention, and mood regulation.
3. Reduced oxidative stress:
   • Antioxidant properties: it can scavenge free radicals and prevent oxidative damage to cells and tissues.
   • Improved mitochondrial function: increasing the efficiency of energy production and reducing the production of harmful free radicals.

Peppermint oil

Peppermint oil is still in use after centuries, here’s why!

Benefits to relief migraines

The menthol in peppermint oil may help relieve pain by relaxing the blood vessels and reducing muscle tension.

1. Pain relief: has a cooling and numbing effect when applied topically
2. Improved circulation in several ways:
   • Vasodilation: improving blood flow and circulation throughout the body, including to the head and neck, where migraines often originate.
   • Nerve stimulation: the menthol has a cooling and soothing effect on the skin, it stimulates nerve endings. This stimulation can help to improve overall circulation by promoting blood flow to the affected area.
   • Anti-inflammatory properties: has anti-inflammatory properties, which means it can reduce inflammation in the body. Inflammation can narrow blood vessels and restrict blood flow, so by reducing inflammation, peppermint oil can help to improve circulation.
3. Reduced muscle tension: has a relaxing effect on the muscles, and by reducing muscle tension, may help relieve migraine symptoms.
4. Improved breathing: has a refreshing and invigorating effect on the respiratory system.

Turmeric

It is a spice that is commonly used in traditional medicine for its potential anti-inflammatory and pain-relieving properties.

Benefits to relieve migraine

Some studies have suggested that turmeric may help relieve migraines, here are a few potential benefits of turmeric for migraines:

1. Anti-inflammatory effects: due to its active ingredient, curcumin. Here’s how it works:
   • Blocking cytokines and enzymes: blocking the production of certain cytokines and enzymes in the body that promote inflammation, such as tumor necrosis factor (TNF) and cyclooxygenase-2 (COX-2).
   • Antioxidant properties: neutralizing harmful free radicals in the body. These free radicals can cause damage to cells and tissues, leading to inflammation.
   • Modulating immune system: modulating the immune system to prevent the overproduction of cytokines and other inflammation-promoting substances.
2. Improved circulation: dilates blood vessels, which can improve blood flow and circulation throughout the body, including to the head and neck, where migraines often originate. Improved endothelial function, endothelial cells line the interior surface of blood vessels and play a critical role in regulating blood flow.
3. Reduced oxidative stress: due to:
   • Antioxidant properties: neutralizing free radicals and prevent oxidative damage to cells and tissues.
   • Upregulation of antioxidant enzymes: stimulating the production of antioxidant enzymes. Superoxide dismutase (SOD) and glutathione peroxidase (GPx), which help to protect against oxidative stress.
   • Inhibition of oxidative pathways: inhibiting certain oxidative pathways in the body that contribute to oxidative stress.
   • Modulation of redox balance: which refers to the balance between oxidants and antioxidants. By maintaining this balance, curcumin can reduce oxidative stress and improve overall health.
4. Pain relief: Curcumin has potent anti-inflammatory effects that can help to reduce pain and swelling.
   • Inhibition of pain pathways: such as the cyclooxygenase (COX) pathway, which is involved in the production of prostaglandins, hormone-like substances that play a role in pain and inflammation.
   • Modulation of nerve signaling: modulating nerve signaling pathways in the body, which play a role in the perception of pain.

Acupuncture

It is a traditional Chinese medicine practice that involves the stimulation of specific points on the body with thin needles. Acupuncture is a traditional Chinese medicine technique that involves the insertion of thin, sterile needles into specific points on the body to relieve various health conditions, including headache and migraine.

Benefits to migraine and dizziness

Here are a few potential benefits of acupuncture for migraines and dizziness:

1. Pain relief: there are several theories to explain its pain-relieving effects:
   • Stimulation of nerve fibers that transmit pain signals, leading to the release of natural pain-relieving substances, such as endorphins and enkephalins.
   • Regulation of the central nervous system, leading to changes in pain perception and modulation of pain signals.
   • Modulation of cytokines, which are proteins involved in inflammation and pain.
2. Improved circulation: The exact mechanism by which acupuncture may stimulate blood flow is not well understood, but there are several theories that have been proposed:
   • Neural mechanism: stimulation of the nerve fibers that increase the release of vasodilatory substances, such as nitric oxide, leading to increased blood flow.
   • Mechanical stimulation: The insertion and manipulation of acupuncture needles may mechanically stimulate blood vessels and increase blood flow.
   • Inflammatory response: which leads to increased blood flow and delivery of oxygen and nutrients to the affected area.
   • Hormonal response: Acupuncture may also stimulate the release of hormones, such as cortisol and adrenaline, which can increase blood flow and help to reduce pain and inflammation.
3. Relaxation: Acupuncture promotes relaxation in several ways:
   • Release of endorphins: natural pain-relieving substances that are produced by the body.
   • Stimulation of the parasympathetic nervous system: which is responsible for slowing down the heart rate and promoting relaxation.
   • Overall relaxation: The process of receiving acupuncture itself can also be relaxing, with the use of soft lighting, soothing music, and a peaceful atmosphere in some clinics.
4. Balancing the nervous system: may help balance the nervous system and restore the flow of energy (also known as Qi) in the body, helping to relieve symptoms of migraine and dizziness.

It’s important to note that while some studies have suggested the above supplements and techniques to help relieve migraines and dizziness, as any other suggestion you need to try for yourself and see what works for you. You can also take a look at a guide for other Migraine Relief options in this Blog.

Collagen

A protein found in our bodies, is mainly responsible for maintaining the structure and strength of various tissues, including the skin, bones, and joints. While collagen is not directly linked to migraine relief, there are a few potential ways in which it could indirectly support overall health, potentially reducing the frequency or severity of migraines in some individuals. Here are a few points to consider:

1. Connective tissue support: Collagen is a crucial component of connective tissues, including those in and around blood vessels. Strengthening these tissues may potentially improve blood flow and reduce the likelihood of certain triggers that contribute to migraines.
2. Anti-inflammatory properties: Chronic inflammation is thought to play a role in migraine development. Collagen contains certain amino acids, such as glycine and proline, which have anti-inflammatory properties. By reducing overall inflammation in the body, collagen may indirectly contribute to migraine management.
3. Gut health improvement: The gut-brain connection is gaining recognition in migraine research. Studies suggest that gut health, including the integrity of the gut lining, can influence migraine frequency. Collagen contains amino acids like glutamine that can support gut health by maintaining the intestinal lining and promoting healing.
4. Nutritional benefits: Collagen supplements often contain other nutrients, such as vitamins and minerals, that can contribute to overall well-being. A well-balanced diet is crucial for general health, and deficiencies in certain nutrients may potentially trigger migraines in susceptible individuals. By improving overall nutrition, collagen supplements might indirectly support migraine management.